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Dr. Greger - Shared by The Pink Paper


How to Boost the Benefits of Exercise

Written by Michael Greger M.D. on August 28th, 2014 

We all know exercise is beneficial to our health. Then why is it that ultramarathon runners may generate so many free radicals during a race that they can damage the DNA of a significant percentage of their cells? Researchers have looked at the exercise-induced increase in free radical production as a paradox: why would an apparently healthy act—exercise—lead to detrimental effects through damage to various molecules and tissues? This arises out of somewhat of a misunderstanding: exercise in and of itself is not necessarily the healthy act—it’s the recovery after exercise that is so healthy, the whole “that-which-doesn’t-kill-us-makes-us-stronger” notion. For example, exercise training has been shown to enhance antioxidant defenses by increasing the activities of our antioxidant enzymes. So, during the race ultra-marathoners may be taking hits to their DNA, but a week later they can experience great benefits, as shown in my video, Enhanced Athletic Recovery Without Undermining Adaptation.

In a recent study, researchers from Oregon State University looked at the level of DNA damage in athletes. Six days after a race, athletes didn’t just go back to the baseline level of DNA damage, but had significantly less, presumably because they had revved up their antioxidant defenses. So, maybe exercise-induced oxidative damage is beneficial, similar to vaccination. By freaking out the body a little, we might induce a response that’s favorable in the long run.

This concept, that low levels of a damaging entity can up-regulate protective mechanisms, is known as hormesis. For example, herbicides kill plants, but in tiny doses may actually boost plant growth, presumably by stressing the plant into rallying its resources to successfully fight back.

Wait a second, though. Could eating anti-inflammatory and anti-oxidant rich plant foods undermine this adaptation response? We know that berries may reduce inflammatory muscle damage (See Reducing Muscle Soreness with Berries), and greens may reduce free radical DNA damage (See Preventing Exercise Induced Oxidative Stress with Watercress). Dark chocolate and tomato juice appear to have similar effects. How it works is that flavonoid phytonutrients in fruits, vegetables, and beans seem to inhibit the activity of xanthine oxidase, considered the main contributor of free radicals during exercise. And the carbs in plant foods may also decrease stress hormone levels.

So in 1999, a theoretical concern was raised. Maybe all that free radical stress from exercise is a good thing, and increased consumption of some antioxidant nutrients might interfere with these necessary adaptive processes. If we decrease free radical tissue damage, maybe we won’t get that increase in activity of those antioxidant enzymes.

A group of researchers who performed a study on tart cherry juice and recovery following a marathon responded to this antioxidant concern by suggesting that, although it is likely that muscle damage, inflammation, and oxidative stress are important factors in the adaptation process, minimizing these factors may improve recovery so we can train more and perform better. So, there are theories on both sides, but what happens when we actually put it to the test?

While antioxidant or anti-inflammatory supplements may prevent these adaptive events, researchers found that blackcurrant extract – although packed with antioxidant and anti-inflammatory properties – actually boosted the health benefits of regular exercise.

If we take antioxidant pills—vitamin C and vitamin E supplements— we can also reduce the stress levels induced by exercise, but in doing so we block that boost in antioxidant enzyme activity caused by exercise. Now maybe we don’t need that boost if we don’t have as much damage, but vitamin C supplements seem to impair physical performance in the first place. With plant foods, though, we appear to get the best of both worlds.

For example, lemon verbena, an antioxidant-rich herbal tea, protects against oxidative damage and decreases the signs of muscular damage and inflammation, without blocking the cellular adaptation to exercise. In a recent study, researchers showed that lemon verbena does not affect the increase of the antioxidant enzyme response promoted by exercise. On the contrary: antioxidant enzyme activity was even higher in the lemon verbena group. In my video, Enhanced Athletic Recovery Without Undermining Adaptation, you can see the level of antioxidant enzyme activity before and after 21 days of intense running exercises in the control group. With all that free radical damage, the body started cranking up its antioxidant defenses. But give a dark green leafy tea, and not only do we put a kabosh on the damage due to all the phytonutrients and antioxidants, but we still get the boost in defenses—in fact, in this case, the boost was even greater.

Find out more on enhancing athletic recovery in this three-part video series:

1. Reducing Muscle Fatigue with Citrus
2. Reducing Muscle Soreness with Berries
3. Preventing Exercise-Induced Oxidative Stress With Watercress

Then there’s my 15-video series on using nitrate-rich vegetables to boost athletic performance starting with Doping With Beet Juice and ending with So Should We Drink Beet Juice or Not?

-Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live year-in-review presentations Uprooting the Leading Causes of Death, More Than an Apple a Day, and From Table to Able.

The PInk Paper shares Dr. Greger


The PInk Paper shares Dr. Greger








Tags: antioxidants,beansberriesbeveragescherrieschocolatecurrantsDNA damageexerciseflavonoidsfruitfruit juicegreensherbal teahormesisinflammationjuicelemon verbenamuscle healthmuscle inflammationoxidative stressplant-based dietssupplementsteatomato juicetomatoesvegansvegetablesvegetariansvitamin Cvitamin E


Breath Awareness Meditation - Dr. Andrew Weil


  1. Let all air out through your mouth
  2. Place tongue on roof of your mouth behind front teeth and hold there
  3. Breathe in through your nose to the count of 4
  4. Hold the breath to the count of 7
  5. Exhale through your mouth to the count of 8
  6. Repeat for 4 breath cycles
  7. Do this exercise 2x per day


Health Benefits of Yoga:Move More for health. The Pink paper offers exercise tips, videos and more.

  1. Increased Flexibility - Stretches muscles and soft tissue,  increases range of motion
  2.  Increased Strength - All types of yoga
  3. Improved Posture - Increases flexibility, strength and awareness help posture
  4. Improved Balance - Especially important as you get older
  5. Improved Joint Health - More mobility, less pain
  6. Better Muscle Tone - Helps shape long, lean muscles
  7. Better Breathing - Both physical and mental benefits
  8. Helps Mood - Focused breathing decreases anxiety, increases relaxation and lessens feelings of stress
  9. Helps Heart - Slows heart rate, lowers blood pressure, decreases cholesterol levels
  10. Relieves - Pain, asthma symptoms, insomnia, arthritis, "the blues"

Safety: For most people yoga is a beneficial form of exercise. Yoga is an excellent way to move more. If you have a pre-existing medical condition or are pregnant consult with your healthcare practitioner before starting a new yoga program. Visit NCCAM for more information. Other safety tips:

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  •  Listen to your body
  • Stay within your limits
  • Yoga is not a competition 
  • Warm-up first
  • Wear comfortable clothing
  • Learn the basics from a qualified, certified Yoga professional

Now you're ready to begin. Before you join a studio or purchase a class card you may want to try a few different types of yoga classes for beginners. Look for yoga studios in your area who offer the first class for free. This is a great way to see if a studio feels right for you. Don't rush. Listen to yourself. Make sure you feel comfortable with the space, the instructor, the class size and other students. If you don't, try another studio. You'll get a lot more out of the experience when you time the time to get the best fit possible. Move more now …you'll thank yourself later. We hope you'll love yoga as much as we do!

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